Race2Recovery, a team of veterans, face more than 4,000km of broken Tarmac and sand dunes during the 18-day Dakar Rally in South America. The soldiers will race for 16 hoursplus a day in a £130,000 custom-built QT Wildcat off-roader, based on a Land Rover Defender.
Each year, only 40 per cent of the hardened competitors manage to complete the gruelling event.
Corporal Tom Neathway, 28, who lost both legs and an arm in a Taliban booby trap in Afghanistan in 2009, will act as navigator during the rally. He said: "I really feel Race2Recovery can show people that, despite facing adversity, illness or injury, it's still possible to do great things."
Their bid to raise money for the military's Tedworth House Personnel Recovery Centre in Wiltshire has won the first grant from a charity set up by Princes William and Harry and the Duchess of Cambridge.
The Endeavour Fund of their Royal Foundation has given £100,000.